Mammary Analogue Secretory Carcinoma Of The Parotid: An Arduous Maze To Solve

نویسندگان

چکیده

Mammary analogue secretory carcinoma (MASC) is an unusual and rare salivary gland malignancy that recapitulates the genetic microscopic features of breast (SCB) which equally entity. MASC SCB express S-100 protein, vimentin, mammaglobin, harbor a t (12; 15) (p13; q25) translocation leads to ETV6-NTRK3 fusion product. The morphology not specific can overlap with many tumors. S100 mammaglobin’s strong positivity confirm diagnosis MASC. along immunohistochemical findings provides important clues for diagnosis. Recent advances in molecular pathology help investigating both differential prognosis oncology. Molecular testing recommended arrive at We report case parotid 47-year-old male patient his profile.t.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mammary analogue secretory carcinoma: A rare salivary gland tumour.

Mammary analogue secretory carcinoma (MASC) is a rare and recently described tumour of the salivary glands. MASC has similar histomorphological and immunohistochemical features of secretory carcinoma of the breast. MASC can be mistaken for other salivary gland tumours, especially acinic cell carcinoma. A 28-year-old man was diagnosed with a rare salivary gland tumour in Pretoria, South Africa (...

متن کامل

Mammary Analogue Secretory Carcinoma of the Soft Palate: A Report of Two Cases

Mammary analogue secretory carcinoma (MASC) is a recently identified salivary tumor that shares morphological features of secretory carcinoma of the breast, salivary acinic cell carcinoma, low grade cystadenocarcinoma and mucoepidermoid carcinoma. To date, a majority of cases have been reported in the major salivary glands with very few seen in the palate. We present 2 single institution cases ...

متن کامل

Mammary Analogue Secretory Carcinoma (MASC) of the salivary gland: A new tumor entity.

Mammary analogue secretory carcinoma (MASC) is a recently described low-grade malignant tumor of the salivary glands, biologically and morphologically equivalent to secretory breast carcinoma. We give a brief overview of this new entity, including morphological, immunohistochemical, molecular-genetic, clinical, epidemiologic features, differential diagnosis, and outcome results.

متن کامل

Finding and Characterizing Mammary Analogue Secretory Carcinoma of the Salivary Gland

BACKGROUND A new tumor entity of the salivary glands, mammary analogue secretory carcinoma (MASC) with ETV6-NTRK3 translocation, has recently been proposed. MASC was originally diagnosed as adenocarcinoma, not otherwise specified (ANOS), or acinic cell carcinoma (AciCC) by the current World Health Organization classification. We aimed to identify MASC cases by molecular tests, and to characteri...

متن کامل

Cytological Features of Mammary Analogue Secretory Carcinoma of the Parotid Gland in a 15-Year-Old Girl: A Case Report with Review of the Literature

Mammary analogue secretory carcinoma (MASC) is a recently recognized tumor of salivary glands characterized by the ETV6-NTRK3 fusion gene. This tumor is very rare in children and adolescents. We report a case of MASC in a 15-year-old girl, the fifth youngest case so far reported. The patient complained of a left infra-auricular mass that gradually enlarged for a year. Fine-needle aspiration cyt...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Indian Journal of Case Reports

سال: 2022

ISSN: ['2454-129X', '2454-1303']

DOI: https://doi.org/10.32677/ijcr.v8i10.3624